What's happening at IRRI
Thursday, October 12, 2017, 01:15pm - 02:15pm
IRRI seminar by Nese Sreenivasulu
October 12, 2017
1:15pm-2:15pm, Havener Auditorium
"What rice scientists can offer to the sugary world ?- Low Glycaemic Index Rice application in Diabetes Prevention and Management"
Author: Dr. Nese Sreenivasulu
Senior Scientist, Grain Quality and Nutrition Center
The world is experiencing an epidemic of diabetes with 450 million incidences and more than 50% of them occur in Asia being the hot spot. Factors driving this epidemic are urbanization associated sedentary lifestyle, higher energy intake through modern diet. Diet plays an important role where rice being the staple food in Asia. Rice lines with slower starch digestibility provide opportunities in mitigating the global rise in type II diabetes and related non-communicable diseases. However, screening for low glycemic index (GI) in rice breeding programs is not possible due to time and cost constraints. This study evaluated the feasibility of using in vitro cooked grain amylolysis, starch mobilization patterns during seed germination, and variation in starch structure and composition in the mature seed to differentiate patterns of starch digestibility. The combination of these biochemical markers can be used as an alternative measure to predict GI. Additionally, transcriptome analysis of stored mRNA transcripts in high and low GI lines detected differences in starch metabolism and confirmed the importance of seed storage pathways in influencing digestibility. Pathway analyses supported by metabolomics data revealed that resistant starch, cell wall non-starch polysaccharides, and flavonoids potentially contribute to slower digestibility. These new insights can guide precision breeding programs to produce low GI rice with acceptable cooking quality to help mitigate the burden of diet-associated lifestyle diseases. Clinical studies evidences have proven that type2 diabetes is not only preventable but curable through intervention of low GI diets enriched with nutrients and fiber. For diabetes prevention, we need to implement novel systems approaches in the promotion of low GI foods and community based effective physical activities to engage population.
The IRRI seminar committee continues to encourage IRRI staff members to present seminars about their work. When preparing the PowerPoint for the seminar, staff members are encouraged to download and use the standard IRRI PowerPoint template. Also, shortly after most seminars have concluded, the audio file and PowerPoint file from the presentation will be available on a special Google Drive, accessible to staff at HQ and in the country offices. Please find Link to Thursday Seminar folders.
IRRI seminars are also a forum for invited guests to present information and their opinions on topics relevant to international rice research and the work of IRRI. Speakers at IRRI Seminars are guests of IRRI and we encourage you to welcome them in every way and engage in polite and constructive discussions with them.
If you have a guest visiting from overseas, or know someone else, who you think would be a suitable candidate to give an IRRI seminar, please email the IRRI seminar committee chair, , to see if they can be fitted into the schedule. The IRRI seminar committee would like to channel all guest and special speakers into the IRRI seminars where possible and we will appreciate your help with this.
Archived versions including video, audio and/or presentation files (e.g. PowerPoint) for most seminars are available to all staff at HQ and in country offices at this Google Drive location shortly after the presentation.
2017 Seminar Committee: Virender Kumar, Paul Quick, Nasreen Khan, Damien Platten, Marichu Bernardo, Rochie Cuevas, and Admin support by Lou Herrero